With the rise of science, philosophers began to question the foundations of knowledge. René Descartes doubted everything except his own consciousness, leading to “I think, therefore I am.” Baruch Spinoza proposed a monistic universe where God and Nature are one, emphasizing rational understanding. Gottfried Wilhelm Leibniz introduced the concept of monads—simple substances that form the fabric of reality.John Locke argued that the mind is a blank slate, with knowledge coming from experience. George Berkeley suggested that existence is perception, and David Hume doubted causality itself, emphasizing skepticism. Giambattista Vico proposed that humans can only truly understand what they have created, highlighting the importance of history and culture.Immanuel Kant sought a middle ground, suggesting that while our experiences are shaped by innate categories of understanding, we can never know things-in-themselves. Georg Wilhelm Friedrich Hegel introduced the dialectical method of thesis, antithesis, and synthesis, viewing history as the unfolding of the Absolute Spirit.This shift towards epistemology and the nature of mind influenced the development of the scientific method, which is fundamental in programming and AI for building and validating models.